Frequently Asked Questions

Frequently Asked Questions

RYBELSUS® is a prescription medicine taken once daily that, along with diet and exercise, may help lower blood sugar in adults with type 2 diabetes.

You can look up your co-pay and see how much RYBELSUS® will cost you.

For RYBELSUS® to work as planned to lower blood sugar, store RYBELSUS® in a dry place away from moisture and keep tablets in the original blister pack until you are ready to take one.

Take on an empty stomach when you first wake up.

Take with no more than 4 ounces of plain water.

Wait at least 30 minutes before eating, drinking, or taking other oral medications.

RYBELSUS® works best if you eat 30 to 60 minutes after taking it.

RYBELSUS® may not work as planned to lower blood sugar if it’s not taken as directed every day. Talk with your healthcare provider if you have any questions about taking RYBELSUS®.

When taken as instructed every day, RYBELSUS®, along with diet and exercise, may help improve your blood sugar. While taking RYBELSUS®, you may experience some side effects.

The most common side effects of RYBELSUS® may include nausea, stomach (abdominal) pain, diarrhea, decreased appetite, vomiting, and constipation. Make sure to talk with your healthcare provider if you have any questions about side effects.

aCommercially insured patients only. Eligibility and other restrictions apply.

bMessage and data rates may apply. Check with your mobile service provider. Message frequency will be based on your selections. Text HELP to 21848 for help. Text STOP to 21848 to quit. See Terms of Use and Conditions.

Yes! If eligible, you may pay as little as $10 for a 30-day prescription.a

There are 2 ways to get this Savings Offer:

Textb READY to 21848 to get co-pay savings.

Textb READY to 21848 to get co-pay savings.

You can also download a Savings Card online.

You can also download a Savings Card online.

aCommercially insured patients only. Eligibility and other restrictions apply.

bMessage and data rates may apply. Check with your mobile service provider. Message frequency will be based on your selections. Text HELP to 21848 for help. Text STOP to 21848 to quit. See Terms of Use and Conditions.

Texta READY to 21848 to get support through text messages with RYBELSUS® Connect.

Texta READY to 21848 to get support through text messages with RYBELSUS® Connect.

aMessage and data rates may apply. Check with your mobile service provider. Message frequency will be based on your selections. Text HELP to 21848 for help. Text STOP to 21848 to quit. See Terms of Use and Conditions.

Get medicine reminders

Receive helpful information

Receive motivational messages

Call a Certified Diabetes Educator


Give us a call for one-on-one, live support from a Certified Diabetes Educator (CDE)—and to learn more about taking RYBELSUS®.

Call 1-833-ASK-A-CDE (1-833-275-2233)
Monday – Friday, 9:00 am – 6:00 pm ET

Give us a call for one-on-one, live support from a Certified Diabetes Educator (CDE)—and to learn more about taking RYBELSUS®.

Call 1-833-ASK-A-CDE (1-833-275-2233)
Monday – Friday, 9:00 am6:00 pm ET

Take RYBELSUS® the same way, every day

For RYBELSUS® to work as planned to improve blood sugar, take as directed by your healthcare provider.

Pay as little as $10 for a 30-day RYBELSUS® prescriptiona

Check your insurance coverage and learn about ways to save.

aCommercially insured patients only. Eligibility and other restrictions apply.

Support to help you start and stay on RYBELSUS®

RYBELSUS® Connect offers support when and where you need it. Textb READY to 21848 to get started.

bMessage and data rates apply. Check with your mobile service provider. Message frequency will be based on your selections. Text HELP to 21848 for help. Text STOP to 21848 to quit. See Terms and Conditions.

aCommercially insured patients only. Eligibility and other restrictions apply.

bMessage and data rates may apply. Check with your mobile service provider. Message frequency will be based on your selections. Text HELP to 21848 for help. Text STOP to 21848 to quit. See Terms of Use and Conditions.