Once-daily RYBELSUS® is a prescription medicine used along with diet and exercise to improve blood sugar in adults with type 2 diabetes. Scroll below to "What is RYBELSUS®?" for Limitations of Use.
Getting on the right RYBELSUS® dose
- The starting dose is 3 mg for the first 30 days to help your body get used to the medicine
- After 30 days, you will be prescribed the 7 mg dose to help lower blood sugar
- If more blood sugar control is needed after at least 30 days on the 7 mg dose, your healthcare provider may prescribe the 14 mg dose
To get the most out of RYBELSUS®, you need the right dose. Remember to pick up your next prescription from your pharmacy.
For RYBELSUS® to work as planned to lower your blood sugar:
- Take on an empty stomach when you first wake up
- An empty stomach means no food, drink, oral medicines, vitamins, or supplements
- Take with no more than 4 ounces of water
- Take RYBELSUS® with a sip of plain water, no more than 4 ounces
- Wait 30 minutes before eating, drinking, or taking other oral medicines
- After 30 minutes, you can eat, drink, or take other oral medicines, vitamins, or supplements
If you miss a dose, the missed dose should be skipped, and the next dose should be taken the following day.
Find answers to frequently asked questions.
How you store RYBELSUS® is key
The blue cap on the RYBELSUS® bottle helps protect your tablets so they can work as planned to lower your blood sugar. Keeping the blue cap tight helps your pills work right.
Store tablets in the closed RYBELSUS® bottle until ready to take one.
Do not use a pill organizer or other container to store tablets.
Swallow tablet whole. Do not cut, crush, or chew.
- Store RYBELSUS® at room temperature between 68°F and 77°F (20°C to 25°C)
- Store in a dry place away from moisture
- Keep RYBELSUS® and all medicines out of the reach of children
Common side effects of RYBELSUS®
- The most common side effects of RYBELSUS® may include nausea, stomach (abdominal) pain, diarrhea, decreased appetite, vomiting, and constipation
- Nausea, vomiting, and diarrhea are most common when first starting RYBELSUS® and when your dose increases
- If you experience side effects that bother you or do not go away, talk to your healthcare provider
Here are some general tips for nausea that may be helpful:
Eat bland, low-fat foods, like crackers, toast, and rice
Eat foods that contain water, like soups and gelatin
Avoid fried, greasy, or sweet foods
Avoid lying down after you eat
Go outdoors for fresh air
Slowly eat smaller, more frequent meals
Drink clear or ice-cold drinks
Save on RYBELSUS® and get personalized support
Visit SaveOnR.com to download a Savings Card. If eligible, pay as little as $10 for a 1-, 2-, or 3-month supply.a
Textb READY to 21848 to get messages to help you start and stay on RYBELSUS®.
Call 1-833-275-2233 for live support from a Diabetes Health Coach M – F, 9:00 AM – 6:00 PM ET. Your FREE Diabetes Health Coach is available via phone, text, or email and is there to help:
- Assist you with the Savings Offer
- Motivate you to set and reach your goals
- Answer your questions one-on-one
- Provide healthy eating and exercise tips
aTo receive offer, 7 mg or 14 mg dose prescription must be for a 1-, 2-, or 3-month supply. For 3 mg dose, pay as little as $10 each month. Eligible, commercially insured patients with product coverage only. Maximum savings of $300 per 1‑month supply, $600 per 2‑month supply, or $900 per 3‑month supply. Eligibility and other restrictions apply.
bMessage and data rates may apply. Check with your mobile service provider. Message frequency will be based on your selections. Text HELP to 21848 for help. Text STOP to 21848 to quit. See Terms and Conditions of Use.
Many people are taking RYBELSUS®, along with diet and exercise, to help improve their A1C. Check out their inspiring stories!
RYBELSUS® patient shown is a paid spokesperson for Novo Nordisk.
